Special Note Regarding Forward-Looking Statements

Our website, press releases, social media posts and other communications contain or may contain forward-looking statements as defined in Section 27A of the Securities Act of 1933, as amended (the “Securities Act”), and Section 21E of the Securities Exchange Act of 1934, as amended (the “Exchange Act”), that involve significant risks and uncertainties. All statements other than statements of historical facts are forward-looking statements. These forward-looking statements include information about our possible or assumed future results of operations or our performance. Words such as “may,” “might,” “will,” “could,” “would,” “should,” “expects,” “intends,” “plans,” “believes,” “anticipates,” “estimates,” “potential,” “continue,” “ongoing,” “targets,” “possible,” “project,” and “predict” and variations of such words and similar expressions are intended to identify the forward-looking statements. Forward-looking statements on our website, press releases, social media posts and other communications may include, for example, statements about: (1) our financial performance, including estimates regarding cash runway, future revenue, expenses, capital requirements, financial condition and need for additional financing; (2) the initiation, enrollment, timing, progress and results of current and future clinical trials; (3) timing and outcome of our research and development programs; (4) timing and likelihood of regulatory interactions, submissions and approvals, as well as commercial outcomes; (5) our expectations regarding the potential market size and the size of the patient populations for our product candidates, if approved for commercial use, and our ability to compete in such markets; (6) expected benefits and strategic advantages of our business and scientific approach and technology; (7) the potential safety and efficacy of our product candidates; (8) our ability to successfully develop, advance, and partner or commercialize our pipeline of product candidates as well as other expansion plans and opportunities; (9) the effectiveness and profitability of our collaborations and partnerships, our ability to maintain current collaborations and partnerships and enter into new collaborations and partnerships; and (10) expectations related to future milestone and royalty payments and other economic terms under our collaborations and partnerships.

These forward-looking statements are based on information available as of the date of the relevant communication or publication, and current expectations, forecasts and assumptions, and involve a number of judgments, risks and uncertainties. Accordingly, forward-looking statements should not be relied upon as representing our views as of any subsequent date, and we do not undertake any obligation to update forward-looking statements to reflect events or circumstances after the date they were made, whether as a result of new information, future events or otherwise, except as may be required under applicable securities laws. Accordingly, you should not place undue reliance on these forward-looking statements in deciding to invest in our securities. As a result of a number of known and unknown risks and uncertainties, our actual results or performance may be materially different from those expressed or implied by these forward-looking statements. You should refer to the “Risk Factors” sections of our filings with the U.S. Securities and Exchange Commission for a discussion of important factors that may cause our actual results to differ materially from those expressed or implied by our forward-looking statements. As a result of these factors, we cannot assure you that the forward-looking statements in our publications and communications will prove to be accurate. Furthermore, if our forward-looking statements prove to be inaccurate, the inaccuracy may be material. In light of the significant uncertainties in these forward-looking statements, you should not regard these statements as a representation or warranty by us or any other person that we will achieve our objectives and plans in any specified time frame, or at all. We undertake no obligation to publicly update any forward-looking statements, whether as a result of new information, future events or otherwise, except as required by law. You should, therefore, not rely on these forward-looking statements as representing our views as of any date subsequent to the date of the relevant publication or communication.

In addition, statements that “we believe” and similar statements reflect our beliefs and opinions on the relevant subject. These statements are based on information available to us as of the date of of the statement. While we believe such information provides a reasonable basis for these statements, such information may be limited or incomplete. Our statements should not be read to indicate that we have conducted an exhaustive inquiry into, or review of, all relevant information. These statements are inherently uncertain, and you are cautioned not to unduly rely on these statements.