Anthony Rosenberg has served as Chairman of the board of directors of Oculis since April 2018. Since April 2015, Mr. Rosenberg has served as the Chief Executive Officer of TR Advisory Services GmbH. Additionally, from April 2015 to April 2020, Mr. Rosenberg served as a Managing Director of MPM Capital. Prior to that, from 2005 to 2012, Mr. Rosenberg held a series of business development and licensing positions of increasing seniority at Novartis, and most recently, from 2012 to 2015, Mr. Rosenberg served as the Corporate Head of M&A and Licensing at Novartis International AG. Mr. Rosenberg currently serves on the boards of directors of Argenx BV, SiO2 Materials Science, and Cullinan Oncology. Mr. Rosenberg previously served on the boards of directors of TriNetX and Radius Health, Inc. Mr. Rosenberg holds a B.Sc. (Hons) from the University of Leicester and a M.Sc. in Physiology from the University of London.

Arni Blöndal has served as a member of the board of directors of Oculis since August 2016. Since February 2013, Mr. Blöndal has served as the Founder and Managing Director of Brunnur Ventures. Prior to that, from November 2010 to February 2013, Mr. Blöndal served as the Founder and Managing Partner of Moneta. Before that, from April 2019 to November 2010, Mr. Blöndal served as a Director, Corporate Finance of Askar Capital. Prior to that, from January 2006 to December 2008, Mr. Blöndal served as a Director, Corporate Finance of LBI hf. Before that, Mr. Blöndal served as the Managing Director of Uppspretta Icelandic Capital Venture SA, an investment company managed by Kaupthing Bank, listed on the Luxembourg Stock Exchange. Prior to that, from November 1999 to January 2001, Mr. Blöndal served as the Managing Director and board chairman of Bepaid UK, Ltd. Before that, from January 1998 to November 1999, Mr. Blöndal served as a Financial Analyst Treasury of Kaupthing Bank. Prior to that, Mr. Blöndal served as a Data Analyst of Hagvangur. Mr. Blöndal currently serves as a member of the board of directors of Laki Power. Mr. Blöndal previously served on the boards of directors of DTE, Atmo Select and Ghostlamp. Mr. Blöndal holds a C.Sc. degree in Engineering from the University of Iceland and a M.Sc. degree in Information Technology from the Technical University of Denmark.

Bart Dzikowski has served as a member of the board of directors of Oculis since May 2019. Since 2009, Mr. Dzikowski has been employed by Novartis International AG, most recently as Managing Director, Head of Transactions & Legal at the Novartis Venture Fund. Prior to that, from 2006 to 2009, Mr. Dzikowski served as a Vice-President at the Investment Banking Division of Bank of America Merrill Lynch. Before that, from 2002 to 2006, Mr. Dzikowski served as an Associate at Allen & Overy LLP. Mr. Dzikowski currently serves on the boards of directors of Enterprise Therapeutics Holdings Limited and UZH Life Sciences Fund AG. Mr. Dzikowski previously served as a member of the board of directors of Enterprise Therapeutics Ltd. and Inflazome Ltd. Mr. Dzikowski holds a B.A. (Hons.) in History from Queen’s University, a J.D. / B.C.L. in Law from McGill University, and is a member of the New York State Bar. We believe that Mr. Dzikowski is qualified to serve as a member of our board of directors due to his extensive experience in law, transactions, venture capital, and the life sciences industry. Mr. Dzikowski has notified us that he will resign from our Board immediately prior to the effectiveness of the registration statement of which this prospectus forms a part.

Florent Gros has served as a member of the board of directors of Oculis since July 2022. Since 2022, Mr. Gros has served as Venture Partner Health Fund II of Earlybird Venture Capital. Additionally, since 2019, Mr. Gros has served as CEO and Founder of Handl Therapeutics and as Managing Partner of Swissvention Partners GmbH, and since 2020, Mr. Gros has served as Chairman & Founder of Amyl Therapeutics, CEO and founder of Priothera Ltd and director of public company Captor Therapeutics. Before that, from 2000 to 2019, Mr. Gros held roles of increasing responsibility at Novartis, including as IP Head Biologics, Head IP Transactions, IP Site Head, and most recently, from 2007 to 2019, Mr. Gros served as Managing Director of Novartis. Before that, from 1998 to 2000, Mr. Gros served as Head IP of Pasteur Mérieux Connaught. Prior to that, from 1993 to 1998, Mr. Gros served as Patent Attorney at Nestlé. Mr. Gros currently serves as a member of the board of directors of Captor Therapeutics SA, Imcheck, and Amyl Therapeutics. Mr. Gros holds a B.Sc. in Biology from the University of Strasbourg, a M.Sc. in Biotechnology Engineering from ESBS, a CEIPI (IP Law) from IUT Robert Schuman, a Master degree in Private Law from the University of Mulhouse, and an MBA from Kaufmann Fellowship. Additionally, Mr. Gros is a French and European qualified patent attorney.

Rob Hopfner, Ph.D., has served as a member of the board of directors of Oculis since January 2018. Since October 2017, Dr. Hopfner has served as the Managing Partner of Pivotal bioVenture Partners. Prior to that, Dr. Hopfner held roles of increasing responsibility at Bay City Capital, and most recently, from October 2009 to September 2017, as the Managing Director and Partner. Before that, from October 2003 to October 2006, Dr. Hopfner served as an Analyst/Associate of the Nutrition and Agribusiness Fund (NANAF). Dr. Hopfner currently serves on the boards of directors of Inozyme Pharma, Vaxcyte, RallyBio Corporation, Evommune, and Plexium. Dr. Hopfner previously served either as a member or observer of the boards of directors of Aciex Therapeutics, Civitas Therapeutics, Cydan, Dermira, Hyperion Therapeutics, Imara Pharmaceuticals, NextWave Pharmaceuticals, Pharmakea Therapeutics, and Vtesse. Dr. Hopfner holds a B.Sc. in Pharmacy from the University of Saskatchewan, a Ph.D. in Pharmacology from the University of Saskatchewan, and an MBA from the University of Chicago Booth School of Business.

Riad Sherif, M.D., has served as the Chief Executive Officer and Director of Oculis since December 2017. Previously, from June 2016 to September 2017, Dr. Sherif served as Entrepreneur in Residence at the Novartis Venture Fund. Before that, Dr. Sherif served as the President of Europe, Middle East and Africa of Alcon, Inc. from March 2014 to May 2016. Prior to that, from January 2002 to April 2014, Dr. Sherif held roles of increasing responsibility at Novartis AG, including as the Global Sales Head in the Transplant and Infectious Disease unit, as the Head for Latin America in transplant and infectious disease, as the President of the Novartis Vaccines and Diagnostics Division for Latin America, and most recently as the President of Novartis Pharmaceuticals, Canada. Prior to Novartis, Dr. Sherif worked for several pharmaceutical companies, holding positions of increasing seniority, mainly in marketing and general management with international scope. Dr. Sherif currently serves as a member of the board of directors of Revenio Group corporation. Dr. Sherif previously served as the Vice Chairman for the Innovative Medicine Canada Association, as the Chairman of In-Vivo Montreal, and as the Chairman of the Board Ophthalmic Surgery and Vision Care of Eucomed. Dr. Sherif is a Medical Doctor by training, and holds an MBA from IMD Business School and a Specialized Master’s Degree in Medical Management from ESCP.

Henry Skinner, Ph.D., has served as a member of the board of directors of Oculis since January 2019. Since March 2021, Dr. Skinner has served as the Chief Executive Officer of the AMR Action Fund. Prior to that, from October 2017 to March 2021, Dr. Skinner served as the Senior Vice President, Venture of Tekla Capital Management LLC. Before that, from November 2008 to October 2017, Dr. Skinner served as the Deputy Head and Managing Director of the Novartis Venture Fund. Prior to that, from 2006 to 2008, Dr. Skinner served as the Executive Director and Head Strategic Alliances, Therapeutics of the Novartis Institutes for BioMedical Research. Before that, from April 2005 to July 2006, Dr. Skinner served as the Chief Executive Officer of SelectX Pharmaceuticals, Inc. Before that, Dr. Skinner served as the President and Chief Executive Officer of NeoGenesis Pharmaceuticals, Inc. Prior to that, from 1997 to 2003, Dr. Skinner held roles of increasing responsibility at Pfizer, including as a Director Technology Acquisitions and Senior Director. Before that, from 1995 to 1997, Dr. Skinner served as a Director Business Development of Lexicon Genetics. Dr. Skinner holds a B.S. and a M.S. in Biology / Biotechnology from Worcester Polytechnic Institute, a M.S. in Biochemistry and a Ph.D. in Microbiology from the University of Illinois, and a M. Jur. in Health Care Law and Policy from Texas A&M University. Dr. Skinner was a postdoctoral fellow at Baylor College of Medicine in the department of Human and Molecular Genetics.